Yet a study published online this week in Science provides more support that inhibiting immune metabolism can quell human diseases. The work centers on a drug, dimethyl fumarate, that has already received approval from the U.S. Food and Drug Administration as a treatment for multiple sclerosis. Although researchers knew that the drug suppresses immune cells, they weren’t sure how. A team led by scientists at Johns Hopkins now reports that the compound cripples an enzyme necessary for glycolysis, bolstering the idea that the pathway can be targeted by drugs. Read more.